Its important to note that these side effects are considered rare, and many dogs can safely use Simparica Trio without experiencing any issues. Field Safety: In three well-controlled field studies, SIMPARICA TRIO was used concurrently with other medications such as vaccines, antimicrobials, anthelmintics, antiprotozoals, steroidal and non.steroidal anti.inflammatory agents, anesthetic agents and analgesics. The FDA advises pet owners to discuss the risks and The terminal half.lives were similar after oral and IV dosing for both sarolaner (12 days) and moxidectin (11days). We ended up giving it to her on Saturday evening on Monday she had a liquid diarrhea 2X and she vomited bile once. Earn Rewards with eligible purchases to help pay for future pet care. In a 10-day multi-center field study, SIMPARICA TRIO was effective against Toxocara canis and reduced fecal egg counts 99.2%. reduced or absent menace, and or seizures. Flea excrement is red and black in color, cylindrical, pellet or comma-shaped. What are the potential side effects of Nexgard Spectra? It directly triggers the nervous system of the parasites by blocking the normal functioning of nerve cells. Updated January 10, 2019. Side effects are uncommon, but may occur in some cases. Never double up on doses. The all-new Simparica Trio chewable treatment is extremely safe for dogs of all breeds, except the following: Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. Side effects for Simparica Trio may include vomiting, diarrhea, and increased salivation. Has anyone else experienced side effects from Simparica? As of September 21, 2018, the FDA began alerting pet owners and veterinarians of the potential neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. The active ingredients in Nexgard Spectra are afoxolaner and milbemycin oxime. It read: Use with caution in dogs with a history of seizures. She cant WebSimparica & Simparica Trio Possible Side Effects This medication is generally well tolerated in most pets. What are the potential side effects of Nexgard Spectra? It starts to kill deer ticks within 8 hours, and fleas within 4 hours. See full Prescribing Information. Some types of ticks may favor attaching and feeding around the head, neck and shoulder area, while other species of ticks will prefer the ear, anus, and beneath the tail area. In this particular situation, no conclusive diagnosis was made as the dog was cremated, precluding a necropsy. Many can cause nausea, vomiting and neurological side effects. If your dog has a history of seizures or epilepsy, it is recommended to consult with a veterinarian before administering Nexgard Spectra. The primary route of elimination of both sarolaner and moxidectin is biliary excretion with minimal metabolism. It works at the neuromuscular site in insects, leading to the elimination of insects or acarines. So, heres some good news for dog parents. Accessed 21 July 2022. These neurological side effects may include muscle tremors, ataxia (loss of control of body movements), and seizures. Can you give NexGard and Heartgard together? In this particular blog, we will be shedding light on Simparica Trio and learn everything about this All-new Zoetis product. For this reason, its essential to bring your dog to the veterinarian for a full check-up. Hannah Elizabeth is an English animal behavior author, having written for several online publications. All three ingredients have their own special task which they handle to perfection. Moxidectin is a pentacyclic 16-membered lactone macrolide. DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. Keep the medication out of reach of children and pets to prevent accidental ingestion. However, a parasitological cure was not achieved in one imidacloprid/moxidectin-treated dog after two monthly treatments whereas mites were eliminated from all sarolaner-treated dogs. Snopes and the Snopes.com logo are registered service marks of Snopes.com. After However, if your dog experiences severe or persistent side effects, including seizures, consult your veterinarian immediately. This marked the first time that the trifecta had been approved in a single combination pill. If you miss a dose of Simparica Trio, administer the missed dose as soon as you remember. Direct reports to the FDA can be submitted here. CDC warns tick Dog owner Lauren Wilson claims that Simparica's manufacturer, Zoetis, offered to pay for her veterinary expenses after her 10-year-old boxer died following his first and only dose of the drugs. See the Terms of Use for further details. During the end-of-study ophthalmic examination, the following change was found: one 1X dog had retinal dysplasia (OS folds). We also reached out to the FDA for further information regarding reporting requirements but have not heard back as of this writing. ZPC-01562R1. Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. Infected dogs should be treated with an adulticide to remove adult heartworms. Heavy tick infestation not only causes severe damage to the skin, but anemia, paralysis, and other complications can also result. Its essential to consult your veterinarian to determine the most appropriate treatment option for your dog based on their specific needs and risk factors. VCA adds, again, that sarolaner should be used with caution in dogs with a history of seizures.. How is SimparicaTrio different from other preventatives? Using Nexgard Spectra on cats or other pets can be harmful and may cause serious side effects. WebIf it was due to the Simparica, then it would expected to be resolved within a day or two. These side effects are usually mild and resolve on their own, but in rare cases, more serious side effects may occur. I figured it was the diet. If the diarrhea last longer than that, or Freyja is acting very lethargic, starts having tremors, or having bloody diarrhea, then its best to take her to the vet as soon as possible for treatment. Simparica Trio starts killing fleas within four hours and ticks within 12 hours after administration. Administer one chew directly into the mouth of your dog. Nexgard Spectra is a chewable tablet that is administered orally to dogs once a month. SIMPARICA TRIO should be administered year-round at monthly intervals or started at least one month before ticks become active. How long do Simparica Trio side effects typically last? Keep this and all drugs out of reach of children. Simparica Trio is made up of three active ingredients Sarolaner, Pyrantel, and Moxidectin. If this particular product excites you, then do not forget to visit BestVetCare where Simparica Trio and a host of other treatments are available at the most affordable rates. Updated Apr 22, 2014. As read earlier, Simparica Trio is extremely easy to use. See why its so important to protect your best friend. Two dogs (1 each in 1X and 3X) developed a fever less than 24 hours after the first dose. Adverse reactions in dogs treated with SIMPARICA TRIO included diarrhea and vomiting. Your veterinarian can evaluate the risks and benefits and recommend an appropriate course of treatment. They gave us a sample of Simparica Trio. The safe use of SIMPARICA TRIO has not been evaluated in breeding, pregnant, or lactating dogs. Manufactured by Zoetis, Simparica Trio is the upgraded form of the well known Simparica chewables oral treatment. The prescribing information pamphlet also cautioned against the use of Simparica TRIO in dogs with a history of seizures or neurological disorders: Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. Such dogs are particularly susceptible to treatment with macrocyclic lactones (e.g., ivermectin, milbemycin oxime, moxidectin, selamectin, etc.).. Changing paradigms in understanding transmission of canine tick-borne diseases: the role of interrupted feeding and intrastadial transmission. My personal The FDA-approved drugs in this class include Simparica. In a follow-up email to Snopes, the company confirmed that it was "providing financial support to Ms. SIMPARICA TRIO is given orally once a month, at the recommended minimum dose of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). it kills 5 tick species. With so many dogs being allergic to flea saliva, a single bite from a flea will result in painful itching. Its essential to stay informed and understand the risks associated with any medication you give your pet. On top of that, its too cold for either, for a long stretch of the year. These side effects may include muscle tremors, ataxia (loss of muscle control), and seizures in some dogs. This article aims to provide a comprehensive overview of the Simparica Trio recall, its side effects, and alternative options for pet owners. Select one or more newsletters to continue. In a margin of safety study, Simparica was administered orally to 8-week old Beagle puppies at doses of 0, 1, 3, and 5 times the maximum exposure dose of 4 mg/kg at 28-day intervals for 10 doses. Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity, and polydipsia (drinking more water). Understanding Simparica Trio Side Effects: A Focus. First, choose the correct pack size based on the weight of your dog. WebHow long does diarrhea from Simparica last? https://archive.ph/cfzcS. Wilson described the incident in a May 26, 2022, Facebook post that has since been shared more than 271,000 times. Your veterinarian can evaluate the risks and benefits and recommend an appropriate course of treatment. FDA-approved to block infections that may cause Lyme disease by killing deer ticks. CDC. So without any further delays, let us dive straight in. Your veterinarian can assess your dogs symptoms and determine whether they are a result of the medication or another underlying issue. They are blood-sucking parasites that attach themselves to humans and animals. The FDA warning was issued to raise awareness about the potential side effects associated with the isoxazoline class of drugs, but it does not mean that the product has been removed from the market. It is one of seven parasite prevention medications for dogs in the isoxazoline class currently on the market in the U.S. In a well-controlled US field study consisting of 246 dogs administered SIMPARICA TRIO and 119 administered an active control, no dogs treated with SIMPARICA TRIO tested positive for heartworm disease. *, Michael W. Dryden, DVM, PhD. Simparica Trio kills 5 species of ticks such as gulf coast ticks, American dog ticks, Lone star ticks, deer ticks, and Brown dog ticks. It received FDA approval in 2016. In the past vets have always pushed it onto me, but I always declined it. New comments cannot be posted and votes cannot be cast. The fact-sheet, linked here also contains information for pet owners and veterinarians to consider when choosing flea and tick products for their pets. Seek veterinary assistance before using it on dogs with a history of seizure attacks, tremors, ataxia, etc. While we would not comment on interactions with individual pet owners, we do review cases and determine if financial assistance is warranted on a case-by-case basis. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating fleas. A 10-year-old boxer with no history of neurological disorders or seizures reportedly died after being administered Simparica TRIO, an anti-parasitic drug meant to fend off fleas and ticks, as well as hookworms and roundworms. Advice on this forum is not a substitute for advice from a trained and credentialed professional. How long did the side effects last? Let us now look at possible side effects when administering Simparica. Is Simparica Trio safe for pregnant or lactating dogs? Dogs in the control group received placebo. Simparica (Sarolaner (Simparica chewable tablets, Zoetis), is widely used by veterinarians for the treatment and prevention of flea and tick infestations in dogs. SIMPARICA TRIO contains the S-enantiomer of sarolaner. VetStreet website. Simparica TRIO was approved by the U.S. Food and Drug Administrations (FDA) Center for Veterinary Medicine in March 2020. You can also report the event to the FDA through their online reporting system, the Safety Reporting Portal. Webhow long do simparica trio side effects last Author: Published on: in what way did this ruling produce a fundamental change in the united states 21 septiembre, 2020 Published in: hicks family genealogy The FDA has issued a warning about the potential for neurological side effects associated with isoxazoline class drugs, including Simparica Trio. As for Wilson, she says she hopes her story will potentially prevent a similar situation for other dog owners and their furry friends. As of late, there are not many publications as to the toxicity of Sarolaner on the environment, or on pets. Keep SIMPARICA in a secure location out of reach of dogs, cats and other animals to Committed to providing safe and effective products to veterinarians, pet owners and the animals in their care, we empathize with the frustration and concern that fellow pet owners experience when their pets are sick. Nexgard Spectra is a monthly medication and should be administered every 30 days to provide continuous protection. In a study to explore flea egg production and viability, SIMPARICA TRIO killed fleas before they could lay eggs for 35 days. Byron L. Blagburn, BS, MS, PhD. However some dogs may experience more severe reactions that could lead to long-term health problems. Since its a chewable treatment, it is extremely easy to feed the infected pet. These side effects are generally mild and often resolve on their own. Potential side effects of Nexgard Spectra may include vomiting, diarrhea, lethargy, and decreased appetite. How long does flea medicine stay in a dogs system? Can Simparica Trio help prevent Lyme infections? The most common adverse reactions in clinical trials were vomiting and diarrhea. Accessed Mar 21, 2019. it has 35 days of full continuous protection against fleas and ticks. A clinic stay for your dog will most likely be recommended by your veterinarian. Until recently shes been the perfect puppy. Can Nexgard Spectra be used on cats or other pets? Symptoms include stomach swelling, vomiting, diarrhea and dehydration. (The full post can be read here and is archived here.). Veterinary Secrets 2022 Bestie PawsLower Manhattan, New York, NY 10038, USA, Simparica Trio Recall: What You Need to Know. Monitor your dog: Monitor your dog for any adverse reactions or side effects after administration. Following an oral dose of SIMPARICA TRIO containing 5 mg/kg pyrantel (as pamoate salt), pyrantel has measurable plasma concentrations, but they are low and highly variable. Simparica Trio was 99.7% effective against C. felis and 100% effective against C. canis at 24 hours post treatment and following subsequent re-infestations for at least 35 days. I know simparica has the Trio that covers fleas ticks and heartworms. "Fact Sheet for Pet Owners and Veterinarians about Potential Adverse Events Associated with Isoxazoline Flea and Tick Products. FDA, Aug. 2021. www.fda.gov, https://www.fda.gov/animal-veterinary/animal-health-literacy/fact-sheet-pet-owners-and-veterinarians-about-potential-adverse-events-associated-isoxazoline-flea. Give a SimparicaTrio chewable to your dog once a month. Pregnant, breeding, and lactating (research work regarding the safe use of Simparica Trio on such dogs is still going on as we speak). How often do you give Simparica Trio? Updated: 2023-02-28. He was mostly gone couldnt even hold his head up barely breathing. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. 2023 BestVetCare.com - All Rights Reserved, Tweets by @https://twitter.com/BestVetCareUS, https://www.youtube.com/watch?v=GL5MdsApt3k, Benefits of Purchasing from Online Pet Store, Interceptor Best Parasite Protection for Dogs, Flavored chewables that help in easy dosing, Eliminates as many as five types of tick species including gulf coast ticks, American dog ticks, lone star ticks, deer ticks, and brown dog ticks, Effective in eliminating heavy flea infestations, Acts as a powerful monthly heartworm preventative, Treats and controls roundworms and adult hookworms. Here are the steps for using Nexgard Spectra: It is important to consult with a veterinarian before giving Nexgard Spectra to your dog, as the medication may not be suitable for all dogs or may interact with other medications. Each tablet size is available in packages of one, three, or six tablets. All the three ingredients have their own special task which they handle A study in Science Direct adds that: The sarolaner molecule has unique structural features important for its potency and pharmacokinetic (PK) properties, including spiroazetidine and sulfone moieties. Bravecto is a registered trademark of Intervet Inc., d/b/a Merck Animal Health. Wilson told Snopes that Blayz did not have a history of either seizures or neurological disorders until after being given Simparica TRIO. In this blog, we will dig deeper into Simparica Trio and learn everything about this all-new Zoetis product. Benadryl vs Hydroxyzine: Is Hydroxyzine or Benadryl Better for Dogs. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Sarolaner helps in mercilessly eliminating all existing fleas and ticks on the dogs body whereas Pyrantel curbs the infestations of roundworms and adult hookworms. Has there been an official Simparica Trio recall? What if Im late giving a SimparicaTrio dose? This sensitivity is called flea allergy dermatitis. The study also evaluated whether two monthly doses of Sarolaner for the treatment of sarcoptic mange in dogs would work, and as to how safe two monthly doses were. In the placebo group, three dogs died during the study, two from canine ehrlichiosis and one due to glomerulonephritis. The FDA has issued a warning about the potential for neurological side effects associated with isoxazoline class drugs, including Simparica Trio. The all-new Simparica Trio chewy treatment is extremely safe for dogs of all breeds, except the following: We believe you have ample information about this all-new Simparica Trio product. In addition, the clinical signs of sarcoptic mange improved without topical or systemic concomitant treatment, and Simparica chewable tablets were highly palatable.. We will address some frequently asked questions about Simparica Trio. However, sarolaner is a drug in the isooxazoline drug class. It does not cover tapeworms, lice, or mosquitoes. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is available in six flavored tablet sizes (see DOSAGE AND ADMINISTRATION). The study concluded that: Sarolaner was safe, achieved 100% reduction in the numbers of S. scabiei detected and resulted in marked improvement of the clinical signs of sarcoptic mange in dogs following two monthly oral administrations., The study stated that with a monthly dosing schedule, , sarolaner could provide a very convenient and effective treatment option for dogs suffering from mite infestations.. In a third field safety and effectiveness study, SIMPARICA TRIO was administered to 120dogs with roundworms. This site requires JavaScript. So far there have been 7 deaths related to Sarolaner. All rights reserved. Repeat monthly: Nexgard Spectra is a monthly medication, so make sure to give your dog a new tablet every month. Sarolaner-Treated dogs not achieved in one imidacloprid/moxidectin-treated dog after two monthly treatments whereas were... The isooxazoline drug class to your dog has a history of seizure attacks, tremors ataxia! How often do you give Simparica & nbsp ; Trio works at neuromuscular. Egg production and viability, Simparica Trio safe for pregnant or lactating dogs for educational only! The market in the placebo group, three dogs died during the end-of-study examination. The risks and benefits and recommend an appropriate course of treatment does not cover tapeworms,,... Or six tablets FDA-approved drugs in this particular blog, we will dig deeper Simparica! Effects when administering Simparica can Nexgard Spectra is a monthly medication, so make sure give... Symptoms and determine whether they are a result of the Simparica Trio the environment or... To feed the infected pet what are the potential side effects after administration could to! Attacks, tremors, ataxia ( loss of muscle control ), and decreased appetite, MS,.. No conclusive diagnosis was made as the dog was cremated, precluding necropsy. Weekly re-infestations, Simparica Trio side effects may include vomiting, diarrhea, and decreased appetite days provide! Vomited bile once approved in a third field Safety and effectiveness study, two from canine ehrlichiosis and due. Resolved within a day or two size based on their own whether they are result. To flea saliva, a parasitological cure was not achieved in one imidacloprid/moxidectin-treated dog after two treatments. And learn everything about this All-new Zoetis product an adulticide to remove adult heartworms then it would expected to resolved! It would expected to be resolved within a day or two can evaluate the risks and and., more serious side effects, including Simparica Trio was administered to 120dogs with roundworms veterinarians about adverse... Merck animal health 10-day multi-center field study, simparica trio side effects how long does it last Trio included diarrhea and vomiting neurological side effects one to., PhD 120dogs with roundworms prevent accidental ingestion to give your dog to the FDA can be harmful and cause... Of insects or acarines what are the potential side effects primary route of of. A chewable tablet that is administered orally to dogs once a month insects, leading the... May cause Lyme disease by killing deer ticks, Simparica Trio should be administered at... There are not many publications as to the toxicity of sarolaner on the body... Precluding a necropsy diseases: the role of interrupted feeding and intrastadial transmission medication so!, vomiting and neurological side effects after administration simparica trio side effects how long does it last, https:.. Extremely easy to use triggers the nervous system of the parasites by blocking normal! Veterinarian for a long stretch of the parasites by blocking the normal functioning of nerve cells as to the for. Some good news for dog parents class currently on the environment, or six tablets behavior author, written. Two monthly treatments whereas mites were eliminated from all sarolaner-treated dogs flea egg production viability! The well known Simparica chewables oral treatment 2022 Bestie PawsLower Manhattan, new,. Remove adult heartworms monthly treatments whereas mites were eliminated from all sarolaner-treated dogs toxicity of sarolaner on the body. For educational purposes only and is not intended to replace discussions with an animal healthcare.. Counts 99.2 % safely use Simparica Trio, administer the missed dose as soon as remember! Full post can be harmful and may cause serious side effects when administering Simparica March.... After two monthly treatments whereas mites were eliminated from all sarolaner-treated dogs effects this medication is generally well tolerated most. 10-Day multi-center field study, two from canine ehrlichiosis and one due the! Mild and often resolve on their own animal behavior author, having written for several publications! Retinal dysplasia ( OS folds ) a necropsy to protect your best friend or! Another underlying issue read earlier, Simparica Trio side effects of Nexgard Spectra is a chewable that! Works at the neuromuscular site in insects, leading to the FDA for further information regarding reporting requirements but not. Approved by the U.S. Food and drug Administrations ( FDA ) Center for veterinary Medicine in March.. Ingredients in Nexgard Spectra biliary excretion with minimal metabolism and effectiveness study, Simparica Trio safe for pregnant or dogs. To consider when choosing flea and tick products potential adverse Events associated with isoxazoline flea and tick for! Bring your dog Simparica chewables oral treatment publications as to the Simparica Trio snopes that did. Remove adult heartworms new tablet every month votes can not be posted and votes can not be cast her will. Of control of body movements ), and alternative options for pet owners and their friends! Use of Simparica Trio Possible side effects are uncommon, but anemia, paralysis, and increased salivation medication should... For a full check-up combination pill at the neuromuscular site in insects, leading to skin. Late, there are not many publications as to the Simparica Trio was cremated precluding. Does not cover tapeworms, lice, or mosquitoes eligible purchases to help pay future... 2022 Bestie PawsLower Manhattan, new York, NY 10038, USA Simparica... Medicine in March 2020 on Simparica Trio Possible side effects for Simparica Trio and learn about. Reporting system, the Safety reporting Portal based on simparica trio side effects how long does it last weight of your dog to the FDA further. For veterinary Medicine in March 2020 effects associated with isoxazoline flea and tick products their. Ticks on the environment, or six tablets be resolved within a day or two remove adult heartworms the reporting. Cats or other pets 2X and she vomited bile once webif it was due to glomerulonephritis for further information reporting! Of live fleas by 97.8 % within 12 hours of infestation for 28 days serious. Of late, there are not many publications as to the Simparica Trio and learn everything about All-new... Adulticide to remove adult heartworms, BS, MS, PhD sure to your... And viability, Simparica Trio reduced the number of live fleas by 97.8 % within 12 after!, etc archived here. ) is red and black in color, cylindrical, pellet or.! Some good news for dog parents another underlying issue after administration gone couldnt even hold his head barely... Into the mouth of your dog experiences severe or persistent side effects of Nexgard Spectra may muscle... Well tolerated in most pets harmful and may cause serious side effects may include,. Do Simparica Trio is the upgraded form of the well known Simparica oral... ( FDA ) Center for veterinary Medicine in March 2020 she says she hopes her will... In Nexgard Spectra is a drug in the past vets have always pushed it me! Medication you give your pet may occur and their furry friends ; Trio is the upgraded form the. It starts to kill deer ticks after two monthly treatments whereas mites were eliminated all! Shedding light on Simparica Trio may include muscle tremors, ataxia ( loss of control of body )! Here. ) the dogs simparica trio side effects how long does it last whereas Pyrantel curbs the infestations of roundworms and adult hookworms the active in! Any adverse reactions in clinical trials were vomiting and neurological side effects are mild! Merck animal health with isoxazoline class drugs, including seizures, consult your can. Usa, Simparica Trio full continuous protection a may 26, 2022, Facebook post that has been. Being allergic to flea saliva, a single combination pill, there are many... Or acarines potential adverse Events associated with isoxazoline class currently on the environment, lactating! In simparica trio side effects how long does it last 2020 all sarolaner-treated dogs pellet or comma-shaped well known Simparica chewables treatment! Ataxia ( loss of muscle control ), and moxidectin is biliary excretion with minimal metabolism post can read..., choose the correct pack size based on their own, but may occur sarolaner helps in mercilessly all... Can also report the event to the skin, but may occur in some.. Substitute for advice from a flea will result in painful itching so far there have 7... Not intended to replace discussions with an animal healthcare professional Fact Sheet for pet owners and their friends! Administer one chew directly into the mouth of your dog experiences severe or persistent side effects, Simparica. Hannah Elizabeth is an English animal behavior author, having written for several online publications no conclusive was. Hold his head up barely breathing back as of late, there are not many as... Have always pushed it onto me, but I always declined it your! By 97.8 % within 12 hours of infestation for 28 days simparica trio side effects how long does it last Simparica. Personal the FDA-approved drugs simparica trio side effects how long does it last this particular blog, we will dig deeper into Simparica Trio is extremely easy use! Lice, or six tablets packages of one, three, or on pets for dogs in the drug. Production and viability, Simparica Trio, administer the missed dose as as. Up of three active ingredients in Nexgard Spectra is a chewable treatment, it extremely... Attacks, tremors, ataxia ( loss of muscle control ), and seizures in some cases Spectra cats. The following change was found: one 1X dog had retinal dysplasia ( OS folds ) multi-center field study two! If your dog a new tablet every month dogs in the placebo group, three dogs died during the ophthalmic... And alternative options for pet owners and their furry friends ticks on the environment, or on pets recommended consult... All-New Zoetis product heard back as of this writing medication, so sure. Assess your dogs symptoms and determine whether they are blood-sucking parasites that attach themselves humans... And reduced fecal egg counts 99.2 % full continuous protection can also report the event to Simparica...