It makes me nervous since I have seen/read plenty of negative things about bravecto and Im also worried to combine bravecto with interceptor. It made my Collies itch nonstop though, so I had to wash it off a day after application. Best of luck with your new girl! ATLANTA Thousands of dog owners worldwide blame a popular flea killer for harming their pets. Adverse reactions are rare, and most dogs take Simparica without any problems. Bear in mind that my opinion is by no means professional, but personally Id go with your first vets prescription. This product should only be used in dogs and puppies over 8 weeks and who weigh more than 2.8 pounds. But I imagine if your vet is recommending it to you, they probably have a pretty good understanding of what tolerances the fleas in your area have developed. Many Rough Collie owners swear by them, and one owner mentioned that she lives in the woods and the Seresto collars kept the ticks off her Roughs. 2022 Collie Chatter. (Same active ingredients in both.) Unlike Nexgard, Bravecto, and Simparica, Credelio had very few (6 reported seizures in as many months) negative reports submitted to the FDA; but it was still mentioned in the FDA report as required to add a precaution to its label because a) its main ingredient is in the -laner family, and b) it is such a new product. But I do think K9 Advantix is a good choice for Collies who arent overly sensitive. I went back and edited my comment for consistency. Simparica tablets are chewable and palatable and readily consumed by dogs when offered by the owner. Unfortunately, both my Collies and to a lesser extent my Aussie mix have some skin sensitivities: so K9 Advantix II and Seresto, while very effective, would most likely cause them skin irritation. As long as I remember to apply it at least once weekly, Ive found it to be very effective. Basically, while the FDA has not pulled these drugs from the market, it has asked the product manufacturers to add precautions to their labels while it continues to monitor information submitted by veterinarians, the companies themselves, and individual product users. . We sometimes see a Smooth Collie named Frank at our local dog park, and Ive been pretty impressed with him. Miscellaneous The other thing is he is small for a male (30 lbs) and the Sentinel dose is for 26-50 lbs, which I think is part of the problem. Im trying to find out if this is safe for her. Its reasonable to think that a larger sample size of dogs would yield greater prevalence of side effects, and a smaller sample size would yield fewer. And its always nice to meet someone, in person or virtually, with another Aussie/Pyrenees cross, especially someone brave (crazy?) This article from Your Dog Advisor gives more natural prevention options and even tells you how to mix your own parasite preventives using essential oils and water. Prior to administration of ProHeart 12, dogs should be tested for existing heartworm infections. My pleasure! I have two Rough Collies who are MDR1 carriers and an Aussie mix, so I have a vested interest in everything Ive researched. Honestly, Id use it even if it was completely ineffective, because it makes my dogs smell delicious. In rare cases, some dogs may have more serious reactions and these pets may do better with a topical or collar flea treatment in the future. Ask the Vet, continued Dogs with the MDR1 mutation may not produce enough of this protein, which can lead to a build-up of drugs in their system, causing toxicity. No one knows yet why some dogs react to isoxazolines like Simparica and others dont, and theres no way to know until its tested on an animal. The topical medicines seem to work best with her, but dont do much to keep the tics at bay. The safe use of SIMPARICA has not been evaluated in breeding, pregnant, or lactating dogs. Its safe for pregnant/nursing mother dogs and puppies as young as eight week. After talking to a variety of Collie people, Frontline seems to be the most trusted of the topical flea/tick products available. (MDR1 -/-) following single oral administration at 5 times the . I have a toy Aussie(Lola), and we are taking her to Mexico this winter and she needs to have certain treatments required by customs to bring her across the border, my vet advised me that Heartguard and Bravecto or Nexguard are safe for her at the correct doses. Wash hands after handling the product. I doubt it as he was on leash and Im always watching him. , Thanks for the reply! What an awesome article. Once WSU has determined your dogs MDR1 status,board- certified veterinary pharmacologistDr. Katrina Mealey, who discovered the MDR1 genetic mutation in dogs and cats, can work with you and your veterinarian through our online portal to determine the best course of action should your pet need to be treated with a medication known to cause adverse reactions. Sounds like shes still going strong at her advanced age, and thats awesome. Thank you! My other vet never brought this up when discussing my MAS. Thank you for your article. My veterinarian, knowing of Yoshis MDR1 gene status, specifically recommended Credelio as a safe option because she was suffering from a terrible flea allergy. collies. Emily is an avid writer, blogger, and Collie lover who collects and posts stories about Collies from around the world. Be prepared to answer questions about whether your dog had a previous history with seizures, has any drug sensitivities, if anything else could possibly have triggered a seizure, and if she has had any seizures since the collar was removed. As such, Prinovoxs 2 active ingredients are Imidacloprid (for fleas, but it doesnt target ticks) and Moxidectin (for heartworm, roundworm, and lungworm). I thought i read some where that I could do a check swab and mail to a certain University . The login page will open in a new tab. Based on Zodiacs ingredients, it should be relatively safe for an Aussie although it may be a bit harsher than some others as the label indicates it should only be used on dogs 6 months or older. However, in such sensitive breeds (which may include, but not necessarily limited to, Collies and related breeds), the recommended dose should be strictly observed. I know it contains Ivermectin, so I am not sure this information is correct. I doubt these would be cheaper than fipronil but it's worth checking. We have an 11 year old tricolor rough coat collie. Im sincerely grateful!! Capstar can be used with heartworm products and some other flea products (see link above for compatibility chart), and it can be given to pregnant or nursing dogs and cats, and even puppies or kittens that are older than 4 weeks or heavier than 2 pounds. Because I am only one person, the medication is relatively new, and it has active ingredients that are the same as more well-known medications that have been known to cause issues for many dogs, I didnt feel that I could give it an entirely glowing recommendation. Consumed by free choice or with food 91.9% of the time See the Simparica Trio difference Compare the labels of other products with Simparica Trio * by killing deer ticks (I didnt find the information about the 6 reported seizures until after I had already given it to my dogs and seen no ill effects from it.) For those who like Advantage but are concerned about ticks on their dogs, the Preventic Tick Collarcan be worn for additional protection. Please let me know how the Wondercide works for you! There are several alternatives to Simparica Trio that can provide similar protection against fleas, ticks, and worms. Emma. It can be used to destroy bedbugs, cockroaches, ants, and even fleas. Im going to order some of the organic spray to help. The manufacturer of Simparica has tested the product for safety in dogs with the MDR1 mutation. Flea allergy dermatitis tends to occur mostly in the late summer. THANK YOU, THANK YOU, THANK YOU! I appreciate the research in this thank you! Giardia can be passed to and cause diarrhea in humans. If you do give Interceptor a try, its best practice to offer it with a meal to help avoid stomach upset. But if youve been using it with no issues, I see no reason not to keep using it! Is Frontline Plus still safe? Just be aware that DE works best when dry, and its effectiveness will be reduced after it gets wet. The Vet is too expensive! Id like to understand why you chose the newer formulation with less external parasitic coverage variety so I can also make the best choice for my pup! The caution is specifically for cats since Advantix contains Permethrin, which is toxic to them. We had a wonderful smooth girl for years and while many of the medication names here sound familiar, I cant remember what we gave her. For years she was taking Sentinel for both heart-worm and tick prevention. According to the Advocate website, the active ingredients are Imidacloprid and Moxidectin. These can come in a few different forms: monthly spot-on, a disposable collar, or a spray. After a single administration of 5 times the maximum recommended dose to this sensitive dog breed, transient Hi Emily, do you know if panacure is a safe wormer? It will make your dog smell absolutely yummy while protecting them from fleas, ticks, black flies, and mosquitoes. Though water resistant, frequent bathing or swimming (once a month or more) will reduce the collars effective time to 5 months or less. I have a cat myself, so I appreciate the information. I like to sprinkle some around the perimeter of my yard and lay an inner circle around the edges of my house which probably looks like Im trying to keep out evil fairies and other fantasy creatures. If you do try it out, please come back here and leave a message to let me know how well it worked for you! We do, however, have lots of deer ticks (also known as black legged ticks). Yoshis vet initially recommended Credelio to us over other oral prescriptions since it is made by Elanco, the same company that makes Interceptor. Congratulations on your new puppy. If youre hoping for a quick, easy skim and just want to know which pest protections are considered safe, Ill list those first under each heading, followed by the use with caution category, and finally the not safe options. Freckles my Aussie/Pyr is such a great dog. Get new post updates in monthly email newsletters. Thank you for this. For long-term arthritis, my vet tech friend has had a lot of success giving her senior dog a regular Glucosamine supplement. MDR1 is the abbreviated name of a gene called Multi-Drug Resistance 1. It is easily administered since it is a flavored chewable, and it takes care of heartworms and fleas. Happy to help! On the down side, it does not cover any ticks. Though not meant for long-term treatment, it is excellent for short-term intervention in the case of severe infestations or for a dog who happened to pick up a few fleas on an outdoor ramble and is in need of some quick relief. Given your knowledge, would you suggest Credelio vs. K9 Advantix II (if tolerated) ? However, heartworm preventatives are still safe for MDR1 drug-sensitive dogs to take at low, FDA-approved dosages. This article (authored by two veterinarians) is an excellent resource for more professional information. Thank you for your article. Dog Flea and Tick Collars. Our team of veterinary pharmacologists provide a current list of medications documented to cause adverse reactions or are strongly suspected to cause adverse reactions in dogs with the MDR1 mutation. From the time that the collar went on the market in 2012 until 2020, the EPA (Environmental Protection Agency) received 1,698 reports of deceased pets. Is Simparica Trio safe for dogs with MDR1? Thats a rough situation, and Im sorry you and your pup are going through this. The majority of canines will be fine, but there are enough who will react. Additionally, it can also be given to cats and even pregnant or nursing animals. Since switching to Bravecto about 1.5 yr ago, zero ticks on either dog! Yet when my Frontline Plus package arrived (I bought it online) the package itself says the product is only good for two types of ticks: dog ticks, and paralysis ticks. Advantage takes care of fleas at all life stages and is even supposed to kill them on contact, and it also covers lice. (Some of the links lead to peer-reviewed scientific articles, so have fun with those if you want the bare, dusty facts.). My thought was to put on a collar in the morning and take it off at night when she will safely be back in the house. Feel free to come back here and share any other information you learn or just to give a puppy growth update. I just picked out a beautiful tri color rough collie this morning! I used Interceptor last year with no issues. It just depends on the individual dog. The drug must be given daily and if more than two days are missed the risk of heartworm infection is significant.. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. These people consider it a bad idea to give any Collie a harsh medication such as Heartgard, even if a genetic test reveals a dog to be normal/normal (clear) of the MDR1 gene. Moxidectin, the heartworm-fighting portion of Advantage, is considered safe if the proper dosage is given monthly, but it did not test as well as either selamectin or milbemycin oxime in clinical trials, though it ranks above Ivermectin. Were bringing home an MDR1 heterozygous smooth boy this weekend so Ill definitely be saving the link to this page. His food hadnt changed, so Im nearly certain it was an adverse reaction to the Credelio. I am so excited. Frontline Shield has Permethrin and Pyriproxifen, so my concern would be that those 2 ingredients together would be stronger and potentially cause skin irritation. Another thing to research and to ask your personal vet about might be potential drug/drug interactions between the Trazadone and Effifax, or whichever parasite preventives you choose to use in the future. But the drug works just like Bravecto and Nexgard it destroys flea and tick nervous systems. Altogether, the agency received 75,000 incident reports, the majority of which were complaints of skin reactions in both animals and humans. Weve had a few puppies come to our local Collie Club gatherings, and weve all really been enjoying them. I dont believe Advocate is marketed here in the US, but in Australia it looks to be Elancos version of Advantage Multi, marketed by Bayer. 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